NEW YORK — New guidelines released Wednesday recommend U.S. adults start colon cancer screening earlier, at age 45 instead of 50.

The American Cancer Society’s advice puts it out of sync with guidelines from an influential government advisory group, which kept the age at 50 in an update two years ago.

Cancer society officials acknowledge the shift to 45 could cause confusion for doctors and patients but felt strongly that they needed to act now. The advocacy group was influenced by its study, published last year, that found rising rates of colon cancer and deaths in people younger than 50. Experts aren’t sure why there has been a 50 percent increase in cases since 1994.

The guidelines are for men and women ages 45 to 75 of average risk for colon cancer; recommendations are different for people with certain conditions, like Crohn’s disease, or a family history of colon cancer. The group endorses six kinds of screening exams, from inexpensive take-home stool tests performed every year to colonoscopies done every 10 years.

“All of these tests are good tests, and the choice should be offered to patients,” said the cancer society’s Dr. Rich Wender. “The best test is the test that gets done.”

The same tests are recommended by the U.S. Preventive Services Task Force, a panel that reviews evidence and issues advice for a variety of screenings and treatments. It updated its colon cancer guidelines in 2016 and its next review isn’t expected until around 2021.

That panel’s recommendations drive what screening is covered by insurance under the Affordable Care Act, although 20 states have laws that link coverage to the cancer society guidelines. It’s not uncommon for groups to have slightly different guidelines, although those for colon cancer have been about the same for many years.

Most colon cancer occurs in adults 55 and older, and the good news is rates of cases and deaths have been falling for decades. Colon cancer, combined with rectal cancer, is the second leading cause of cancer death in the U.S. This year, more than 140,000 Americans are expected to be diagnosed with it, and about 50,000 will die from it.