NEW YORK — The maker of Ambien said Wednesday that “racism is not a known side effect” after Roseanne Barr cited the insomnia drug in explaining the tweet that led ABC to cancel her show.

Hours after ABC pulled the plug on “Roseanne” because of her offensive tweet about former Obama adviser Valerie Jarrett — and quickly breaking a promise to stay off Twitter — the comedian was busy posting on the social media platform.

Barr tweeted that what she did was unforgivable and urged supporters not to defend her. She said of the Jarrett tweet, “It was 2 in the morning and I was ambien tweeting.” The tweet that discussed “ambien tweeting” has been taken down.

hey guys, don’t defend me, it’s sweet of you 2 try, but…losing my show is 0 compared 2 being labelled a racist over one tweet-that I regret even more.

— Roseanne Barr (@therealroseanne) May 30, 2018

I apologize to Valerie Jarrett and to all Americans. I am truly sorry for making a bad joke about her politics and her looks. I should have known better. Forgive me-my joke was in bad taste.

— Roseanne Barr (@therealroseanne) May 29, 2018

The drug maker Sanofi took to social media to say that “while all pharmaceutical treatments have side effects, racism is not a known side effect of any Sanofi medication.”

Barr later tweeted that she has had odd experiences while taking the drug late at night. “I blame myself, not Ambien,” she tweeted.

People of all races, religions and nationalities work at Sanofi every day to improve the lives of people around the world. While all pharmaceutical treatments have side effects, racism is not a known side effect of any Sanofi medication.

— Sanofi US (@SanofiUS) May 30, 2018

After not mentioning Barr’s firing in a campaign-style rally in Tennessee Tuesday night, President Donald Trump broke his silence on Twitter. He noted that Robert Iger, chief executive of ABC parent Walt Disney Co., called Jarrett to tell her that ABC did not tolerate Barr’s comments.

“Gee, he never called President Donald J. Trump to apologize for the HORRIBLE statements made and said about me on ABC,” Trump wrote. “Maybe I just didn’t get the call?”
Trump reveled in the success of “Roseanne” after Barr’s character in the show came out as a supporter of his presidency.

On Wednesday afternoon, White House spokeswoman Sarah Huckabee Sanders said that tweet was meant to point out media bias against him, not support Barr. Sanders faulted some networks for not covering Trump’s signing Wednesday of legislation giving terminally ill patients the right to try unapproved drugs.

Bob Iger of ABC called Valerie Jarrett to let her know that “ABC does not tolerate comments like those” made by Roseanne Barr. Gee, he never called President Donald J. Trump to apologize for the HORRIBLE statements made and said about me on ABC. Maybe I just didn’t get the call?

— Donald J. Trump (@realDonaldTrump) May 30, 2018

She also faulted Iger for not apologizing to Trump after ESPN personality Jemele Hill called Trump a “white supremacist.”

“Roseanne” was an instant hit when it returned this spring after a two-decade hiatus. But after Barr’s tweet that likened Jarrett, who is black and Iranian, to a cross between the Muslim Brotherhood and the “Planet of the Apes,” ABC canceled the show in a one-sentence statement from network entertainment president Channing Dungey. She called it “abhorrent, repugnant and inconsistent with our values.”

Barr’s agent also dropped her and several services pulled “Roseanne” reruns.